Objective: To compare the self-effcacy and self-care ability of persons with stoma, before and after receiving a self-effcacy-promoting programme Design: Two-group quasi-experimental research with a pretest and a posttest Methodology: The subjects of the study were 57 patients who, by prior appointment, received permanent stoma surgery. After being recruited by means of simple random sampling, 29 of the patients were assigned to the control group, which received standard care, whilst the other 28 were assigned to the experimental group, which was given the self-effcacy promoting programme. Data gathering was conducted using a personal information record form, the Stoma Self-Effcacy Scale, and the Stoma Self-Care Ability Scale. Descriptive statistics and t-test were employed for data analysis. Results: First, the experimental group’s post-intervention perceived self-effcacy score was signifcantly higher than its pre-intervention score (by p < 0.05), and signifcantly higher than that of the control group (by p< 0.05). Second, the experimental group scored signifcantly higher on self-care ability than the control group did (by p <0.05). Recommendations: It is recommended that nurses and healthcare teams implement this self-effcacy promoting programme to promote self-effcacy and self-care ability in stoma surgery patients, in the pre-operative, post-operative, and post-discharge stages.